Letting science speak for itself
News & AlertsHighlights Issue 006

Highlights Issue 006

 Outbreak of Unknown Etiology in the Democratic Republic of the Congo 

Updates as of December 17, 2024

A mysterious illness has emerged in a remote region of the Democratic Republic of the Congo (DRC), affecting at least 416 people and resulting in 32 confirmed deaths. Health officials suspect malaria may be a contributing factor, though investigations are ongoing to determine if other diseases are also involved.

According to World Health Organization (WHO) Director-General Dr. Tedros Adhanom Ghebreyesus, 12 initial patient samples were analyzed, with 10 testing positive for malaria. “It’s possible that more than one disease is involved,” he noted. Over the past week alone, 147 new cases have been reported, alongside one additional death, bringing the total fatalities to 32. The most recent death involved a child under the age of 5.

Africa CDC Director Jean Kaseya, MD, MPH, highlighted that nearly 42% of the cases have been reported in children younger than 5 years old. Investigations are ongoing to verify if 44 additional community-reported deaths are connected to this outbreak.

The illness, which some are referring to as “Disease X,” has spread primarily in the Panzi district of Kwango Province. This region is particularly challenging due to its remoteness, poor health infrastructure, and limited communication systems, in addition to recurring military conflict. Travel to the affected area is further hindered by dirt roads that have become impassable due to heavy flooding during the rainy season.

Local vulnerabilities exacerbate the crisis. The Panzi district experiences high levels of malnutrition and low vaccination coverage, leaving children particularly susceptible to diseases like malaria, pneumonia, and measles.

Efforts to combat the outbreak are underway. Teams of laboratory technicians and epidemiologists from the DRC Health Ministry, supported by the WHO and other government partners, are deployed in the field to identify the causative agent and strengthen the response. However, the Panzi health zone, located approximately 700 km (435 miles) from the capital Kinshasa, remains difficult to access, further complicating containment efforts.

The combination of logistical challenges, limited healthcare infrastructure, and a vulnerable population underscores the urgency of addressing this outbreak. Health authorities continue to monitor the situation closely as investigations progress.

https://www.who.int/emergencies/disease-outbreak-news/item/2024-DON546

https://www.cnn.com/2024/12/10/health/democratic-republic-congo-outbreak-malaria/index.html

https://www.cidrap.umn.edu/misc-emerging-topics/cases-rise-unexplained-dr-congo-outbreak-amid-testing-challenges


U.S. Purchases $50 Million Additional Anthrax Vaccines

Published: December 16th, 2024.

https://www.vax-before-travel.com/2024/12/16/us-purchases-50-million-additional-anthrax-vaccines


IDSA AMR Partnership

Published: December 14th , 2024

https://lnkd.in/dXT_X84v


Progress towards poliomyelitis eradication – Afghanistan, January 2023–September 2024

Published: December 13th , 2024

The Weekly Epidemiological Record (WER)


First isolation of the Sindbis virus in mosquitoes from southwestern Spain reveals a new recent introduction from Africa

Published: December 13th, 2024.

https://doi.org/10.1016/j.onehlt.2024.100947


New Dosing Interval and Schedule for the Bexsero MenB-4C Vaccine: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, October 2024

Published: December 12th , 2024

https://www.cdc.gov/mmwr/volumes/73/wr/mm7349a3.htm#:~:text=ACIP%20recommends%20that%20MenB%2D4C,complement%20inhibitor%20use%3B%20microbiologists%20routinely


Press Release: Two combination vaccine candidates (not mRNA vaccines) for prevention of influenza and COVID-19 granted Fast Track designation in the US

Published: December 11, 2024.

https://www.sanofi.com/en/media-room/press-releases/2024/2024-12-11-06-00-00-2995072


Marburg Outbreak in Rwanda Situation Summary

Published: December 10th , 2024.

https://lnkd.in/dDcnbxJK


Epidemiological Alert Measles in the Americas Region – 9 December 2024

https://www.paho.org/en/documents/epidemiological-alert-measles-americas-region-9-december-2024


Mosquito-borne disease has cost the world billions, researchers say.
Scientists say there were 18.7 million chikungunya cases that exacted a total cost of nearly $50 billion over a decade.

Published: December 7, 2024.

https://www.washingtonpost.com/wellness/2024/12/07/mosquito-illness-brazil-cost-chikungunya/


Chikungunya Vaccination Outperforms Medication Treatment ROI

Published: December 6, 2024.

https://www.vax-before-travel.com/2024/12/16/us-purchases-50-million-additional-anthrax-vaccines


Mpox Vaccine Production Could Put Africa First in Line

Published: November 14, 2024.

https://www.sabin.org/resources/mpox-vaccine-production-could-put-africa-first-in-line/

Latest